Human EBI3 Protein, His Tag
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27) . IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
Product Specifications
Background
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27) . IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.3 kDa. The protein migrates as 25-26 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .
Accession Number
Q14213
Expression Region
Arg 21 - Lys 229
Host
E. coli
Target
EBI3
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized Human IL-27 Protein, Fc Tag, premium grade (Cat. No. IL7-H5254) at 10 μg/mL (100 μL/well) can bind Human EBI3 Protein, His Tag (Cat. No. EB3-H51H3) with a linear range of 0.02-0.625 μg/mL (QC tested).
Format
Powder
Buffer
20 mM NaAc, 150 mM NaCl, pH3.5
Additives
Trehalose
Molecular Weight
25.3 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
E. coli
Species
Human
Protein ID
Q14213
Preservative
Trehalose
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