Human NODAL Protein, Tag Free
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. [provided by RefSeq, Aug 2016]
Product Specifications
Background
Specifications
Accession Number
Q96S42
Expression Region
His 238 - Leu 347
Host
E. coli
Target
NODAL
Conjugation
Unconjugated
Tag
Native
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Format
Powder
Buffer
10 mM Sodium citrate, pH3.0
Additives
Trehalose
Molecular Weight
12.9 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
50ug*1
Host or Source
E. coli
Species
Human
Protein ID
Q96S42
Preservative
Trehalose
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