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Human FGF-6 Protein, His Tag

Human FGF-6 Protein, His Tag (FG6-H51H4) is expressed from E. coli cells. It contains AA Gly 41 - Ile 208 (Accession # P10767-1).

Product Specifications

Background

Fibroblast growth factor 6 plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration. For instance, FGF-6 might involve in MSCs proliferation and chondrogenic differentiation. Additionally, FGF-6 were identified as oncogene products. FGF6 is found over expressed in prostatic intraepithelial neoplasia and prostate cancer and promotes the proliferation of the transformed prostatic epithelial cells.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.6 kDa. The protein migrates as 23-25 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Expression Region

Gly 41 - Ile 208

Host

E. coli

Target

FGF-6

Conjugation

Unconjugated

Tag

C-10×His

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized Human FGF-6 Protein, His Tag (Cat. No. FG6-H51H4) at 5 μg/mL (100 μL/well) can bind Human FGF R4, Fc Tag (Cat. No. FG4-H5253) with a linear range of 0.039-1.25 μg/mL (QC tested).

Format

Powder

Buffer

20 mM Sodium Citrate, pH3.0

Additives

Trehalose

Molecular Weight

20.6 kDa

Shipping Conditions

Room Temperature

Storage Conditions

-20°C

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