Human DDC / Dopa Decarboxilase Protein, His Tag (MALS verified)
Dopa decarboxilase (DDC), also known as aromatic amino acid decarboxylase, is a group II decarboxylase. The enzyme catalyzes the decarboxylation of aromatic L-amino acids to produce the corresponding amines. DDC produces the neurotransmitters dopamine and serotonin from L-Dopa and L-5-hydroxytryptophan, respectively. DDC inhibitors is in clinical use to treat Parkinson's disease (PD), usually co-administrated with L-DOPA. DDC would block peripheral conversion to dopamine and allow a greater percentage of L-DOPA to reach the brain, causing an increase in brain dopamine levels, and reducing the side effects of dopamine-rich blood.
Product Specifications
Background
Specifications
Accession Number
P20711-1
Expression Region
Met 1 - Glu 480
Host
Insect Cells
Target
DDC
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Liquid
Buffer
25 mM MES, 150 mM NaCl, pH6.0
Additives
Glycerol
Molecular Weight
55.8 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
20ug*1
Host or Source
InsectCells
Species
Human
Protein ID
P20711-1
Preservative
Glycerol
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