H-Pro-Phe-OH

H-Pro-Phe-OH is a dipeptide containing proline and phenylalanine, which can serve as a substrate for prolinase. H-Pro-Phe-OH can also be used for polypeptide synthesis, where phenylalanine is an aromatic amino acid that can inhibit the activity of Angiotensin-converting enzyme (ACE, HY-P2983) [1][2].

Product Specifications

CAS Number

[13589-02-1]

Product Name Alternative

Pro-Phe

UNSPSC

12352209

Hazard Statement

H302, H315, H319

Target

Angiotensin-converting Enzyme (ACE)

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/h-pro-phe-oh.html

Purity

99.14

Solubility

H2O : 1 mg/mL (ultrasonic)

Smiles

O=C([C@@H]1CCCN1)N[C@H](C(O)=O)CC2=CC=CC=C2

Molecular Formula

C14H18N2O3

Molecular Weight

262.30

Precautions

H302, H315, H319

References & Citations

[1]Majumder K, et al. Angiotensin I converting enzyme inhibitory peptides from simulated in vitro gastrointestinal digestion of cooked eggs. J Agric Food Chem. 2009 Jan 28;57 (2) :471-7.|[2]Priestman DA, et al. Prolinase and non-specific dipeptidase of human kidney. Biochem J. 1985 Nov 1;231 (3) :689-94.