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KRAS inhibitor-24

KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC50 of [1].

Product Specifications

CAS Number

[3030576-47-4]

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kras-inhibitor-24.html

Smiles

FC1=C(C2=CC(O)=CC(Cl)=C2CCCCC(NCC[C@@]3([H])CN4CCC3)=O)N=CC(C1=N5)=C4N=C5OC[C@@]67N(CCC7)C[C@@H](C6)F

Molecular Formula

C33H39ClF2N6O3

Molecular Weight

641.15

References & Citations

[1]James Paul LAJINESS, et al. Pyridopyrimidine kras inhibitors. Patent WO 2024/040131 A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

K-Ras

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