KRAS inhibitor-24
KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC50 of [1].
Product Specifications
CAS Number
[3030576-47-4]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-inhibitor-24.html
Smiles
FC1=C(C2=CC(O)=CC(Cl)=C2CCCCC(NCC[C@@]3([H])CN4CCC3)=O)N=CC(C1=N5)=C4N=C5OC[C@@]67N(CCC7)C[C@@H](C6)F
Molecular Formula
C33H39ClF2N6O3
Molecular Weight
641.15
References & Citations
[1]James Paul LAJINESS, et al. Pyridopyrimidine kras inhibitors. Patent WO 2024/040131 A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
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