(R) -Thionisoxetine (hydrochloride)
(R) -Thionisoxetine hydrochloride (LY-368975 hydrochloride) is a potent and selective central and peripheral norepinephrine (NE) uptake inhibitor. (R) -Thionisoxetine hydrochloride prevents 6-hydroxydopamine-induced hypothalamic NE depletion with an ED50 of 0.21 mg/kg. (R) -Thionisoxetine hydrochloride can be used in the study of a variety of diseases, including depression and urinary incontinence[1].
Product Specifications
CAS Number
222961-65-1
Product Name Alternative
LY-368975 (hydrochloride)
UNSPSC
12352005
Target
Monoamine Transporter
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/r-thionisoxetine-hydrochloride.html
Smiles
CSC1=CC=CC=C1O[C@@H](C2=CC=CC=C2)CCNC.Cl
Molecular Formula
C17H22ClNOS
Molecular Weight
323.88
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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