(E) -Naringenin chalcone

(E) -Naringenin chalcone is an orally active anti-allergic agent. (E) -Naringenin chalcone also has antioxidant, anti-inflammatory activities. (E) -Naringenin chalcone can improve adipocyte functions. (E) -Naringenin chalcone inhibits histamine release from rat peritoneal mast cell[1][2][4].

Product Specifications

CAS Number

[25515-46-2]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/e-naringenin-chalcone.html

Purity

98.87

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC=C1/C=C/C(C2=C(C=C(O)C=C2O)O)=O

Molecular Formula

C15H12O5

Molecular Weight

272.26

Precautions

H315, H319, H335

References & Citations

[1]Taichi Yamamoto, et al. Anti-allergic activity of naringenin chalcone from a tomato skin extract. Biosci Biotechnol Biochem. 2004 Aug;68 (8) :1706-11. |[2]Taro Horiba, et al. Naringenin chalcone improves adipocyte functions by enhancing adiponectin production. Mol Cell Endocrinol. 2010 Jul 29;323 (2) :208-14. |[3]Chiaki Iwamura, et al. Naringenin chalcone suppresses allergic asthma by inhibiting the type-2 function of CD4 T cells. Allergol Int. 2010 Mar;59 (1) :67-73. |[4]Shizuka Hirai, et al. Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages. Life Sci. 2007 Sep 29;81 (16) :1272-9.