3β,7β,15α-Trihydroxy-4- (hydroxymethyl) -11,23-dioxo-lanost-8-en-26-oic acid
3β,7β,15α-Trihydroxy-4- (hydroxymethyl) -11,23-dioxo-lanost-8-en-26-oic acid is a triterpene compound that can be found in Ganoderma lucidum, and it inhibits nitric oxide (NO) production in BV-2 microglial cells induced by lipopolysaccharide (LPS, HY-D1056), with an IC50 of 4.15 μM[1].
Product Specifications
CAS Number
1961358-03-1
UNSPSC
12352211
Target
NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/3β-7β-15α-trihydroxy-4-hydroxymethyl-11-23-dioxo-lanost-8-en-26-oic-acid.html
Smiles
C[C@]12C3=C(C(C[C@@]1([C@@](C[C@@H]2O)([H])[C@H](C)CC(CC(C)C(O)=O)=O)C)=O)[C@@]4([C@@]([C@@](C)([C@H](CC4)O)CO)([H])C[C@@H]3O)C
Molecular Formula
C30H46O8
Molecular Weight
534.68
References & Citations
[1]Jiao Y, et al. Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia[J]. Bioorganic & medicinal chemistry letters, 2016, 26 (15) : 3556-3561.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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