Ludartin
Product Specifications
UNSPSC Description
Ludartin a sesquiterpene lactone, which can be isolated from the plant Artemisia carruthii Wood. Ludartin reduces the expression of myeloperoxidase and malondialdehyde, enhances the expression of glutathione and superoxide dismutase in spinal cord tissue. Ludartin inhibits neuronal apoptosis. Ludartin inhibits the upregulation of tumor necrosis factor-α, interleukin-1β, and interleukin-6. Ludartin improves the motor function of rats with spinal cord injury[1].
Target Antigen
Apoptosis; Glutathione Peroxidase
Type
Natural Products
Related Pathways
Apoptosis;Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ludartin.html
Smiles
C[C@]12[C@]3([H])[C@]4([H])[C@](CCC(C)=C3C[C@@]1([H])O2)([H])C(C(O4)=O)=C
Molecular Weight
246.30
References & Citations
[1]Xu Wei, et al., Ludartin exhibits therapeutic effect on spinal cord injury through inhibition of apoptosis and inflammation[J]. 2019.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126758/Ludartin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126758/
Clinical Information
No Development Reported
CAS Number
36149-87-8
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