Ludartin
Ludartin a sesquiterpene lactone, which can be isolated from the plant Artemisia carruthii Wood. Ludartin reduces the expression of myeloperoxidase and malondialdehyde, enhances the expression of glutathione and superoxide dismutase in spinal cord tissue. Ludartin inhibits neuronal apoptosis. Ludartin inhibits the upregulation of tumor necrosis factor-α, interleukin-1β, and interleukin-6. Ludartin improves the motor function of rats with spinal cord injury[1].
Product Specifications
CAS Number
[36149-87-8]
UNSPSC
12352005
Target
Apoptosis; Glutathione Peroxidase
Type
Natural Products
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ludartin.html
Smiles
C[C@]12[C@]3([H])[C@]4([H])[C@](CCC(C)=C3C[C@@]1([H])O2)([H])C(C(O4)=O)=C
Molecular Formula
C15H18O3
Molecular Weight
246.30
References & Citations
[1]Xu Wei, et al., Ludartin exhibits therapeutic effect on spinal cord injury through inhibition of apoptosis and inflammation[J]. 2019.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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