(Rac) -Enadoline

(Rac) -Enadoline ((Rac) -CI-977 free base) is a selective K-opioid receptor agonist that stereoselectively antagonizes clonic seizures induced by slow intravenous injection of N-methyl-DL-aspartate in mice[1].

Product Specifications

CAS Number

[107431-28-7]

Product Name Alternative

(Rac) -CI-977 (free base)

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rac-enadoline.html

Smiles

O=C(CC1=CC=CC2=C1C=CO2)N(C3C(N4CCCC4)CC5(CCCO5)CC3)C

Molecular Formula

C24H32N2O3

Molecular Weight

396.52

References & Citations

[1]Singh L, et al. The anticonvulsant action of CI-977, a selective κ-opioid receptor agonist: a possible involvement of the glycine/NMDA receptor complex[J]. European journal of pharmacology, 1990, 191 (3) : 477-480.