Aminomethyltrioxsalen (hydrochloride)

Aminomethyltrioxsalen hydrochloride is a derivative of Psoralen (HY-N0053) . Aminomethyltrioxsalen hydrochloride penetrate intact cells and form interstrand crosslinks between pyrimidine residues of nucleic acid helices upon irradiation with ultraviolet light as a bifunctional nucleic acid intercalating agent, which can be used as a probe for double-stranded regions in heterogeneous nuclear RNA (hnRNA) to detect the secondary structure of hnRNA[1].

Product Specifications

CAS Number

[62442-61-9]

UNSPSC

12352005

Hazard Statement

H302, H312, H314, H332, H351

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/aminomethyltrioxsalen-hydrochloride.html

Purity

98.46

Solubility

DMSO : 5.83 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C=C(C)C2=CC3=C(OC(C)=C3CN)C(C)=C2O1.Cl

Molecular Formula

C15H16ClNO3

Molecular Weight

293.75

Precautions

H302, H312, H314, H332, H351

References & Citations

[1]Calvet JP, et al., Heterogeneous nuclear RNA double-stranded regions probed in living HeLa cells by crosslinking with the psoralen derivative aminomethyltrioxsalen. Proc Natl Acad Sci U S A. 1979 Feb;76 (2) :755-9.