YM-60828 (methanesulfonate)
YM-60828 is an FXa inhibitor with antithrombotic properties. In the rat arteriovenous shunt model, YM-60828 does not prolong coagulation time but reduces the levels of thrombin-antithrombin III complex (TAT) in a dose-dependent manner. YM-60828 exhibits only anti-FXa activity and does not show anti-thrombin activity, indicating that its antithrombotic effect is independent of thrombin. Therefore, the antithrombotic effect of YM-60828 can be monitored by TAT[1].
Product Specifications
CAS Number
209187-02-0
UNSPSC
12352005
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ym-60828-methanesulfonate.html
Smiles
O=S(N(CC1=CC=C2C=CC(C(N)=N)=CC2=C1)C(C=C3)=CC=C3OC4CCN(CC4)C(C)=N)(CC(O)=O)=O.O=S(O)(C)=O
Molecular Formula
C28H35N5O8S2
Molecular Weight
633.74
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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