Fluvoxamine (maleate)
Fluvoxamine maleate (DU-23000 maleate) is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.
Product Specifications
CAS Number
61718-82-9
Product Name Alternative
DU-23000 (maleate)
UNSPSC
12352005
Hazard Statement
H302
Target
Serotonin Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Fluvoxamine-maleate.html
Purity
99.81
Solubility
DMSO : ≥ 100 mg/mL|H2O : 20 mg/mL (ultrasonic)
Smiles
O=C(O)/C=C\C(O)=O.FC(C1=CC=C(/C(CCCCOC)=N/OCCN)C=C1)(F)F
Molecular Formula
C19H25F3N2O6
Molecular Weight
434.41
Precautions
H302
References & Citations
[1]Ginsburg, B.C., J.W. Pinkston, and R.J. Lamb, The potency of fluvoxamine to reduce ethanol self-administration decreases with concurrent availability of food. Behav Pharmacol, 2012. 23 (2) : p. 134-42.|[2]Claassen, V., et al., Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor. Br J Pharmacol, 1977. 60 (4) : p. 505-16.|[3]Escalona, R., et al., Fluvoxamine treatment in veterans with combat-related post-traumatic stress disorder. Depress Anxiety, 2002. 15 (1) : p. 29-33.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
EMBO Mol Med. 2022 Jul 7;14 (7) :e15373.|Free Radic Biol Med. 2025 Jan:226:96-108.|Oxid Med Cell Longev. 2021 Jan 4;2021:8836818.|PLoS Negl Trop Dis. 2019 Aug 20;13 (8) :e0007681. |Research Square Preprint. 2023 Aug 10.|Sci Transl Med. 2019 Feb 6;11 (478) . pii: eaau5266.|ACS Omega. 2025 Oct 17;10 (42) :50208-50217.|Int Immunopharmacol. 2024 Jan 25:127:111382.|Int Immunopharmacol. 2025 Jan 6:147:113969.|Mol Med. 2022 Aug 3;28 (1) :87.|Patent. US20250123269A1.|University of South Carolina. 2025.|Viruses. 2022 Jun 23;14 (7) :1369.
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