Mouse SLAMF7 / CRACC / CD319 Protein, Mouse IgG2a Fc Tag, low endotoxin
Mouse SLAMF7 Protein, Mouse IgG2a Fc Tag (SL7-M5252) is expressed from human 293 cells (HEK293) . It contains AA Ala 22 - Gly 224 (Accession # Q8BHK6-1) .
Product Specifications
Background
SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.
Specifications
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 49.4 kDa. The protein migrates as 55-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q8BHK6-1
Expression Region
Ala 22 - Gly 224
Host
HEK293
Target
SLAMF7
Conjugation
Unconjugated
Tag
C-mFc (mIgG2a)
Source
Mouse
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
0.1 EU per μg
Purity
95%
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, pH7.5
Additives
Trehalose
Molecular Weight
49.4 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/SL7-M5252.pdf
Species
Mouse
Curated Selection
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