Human Neutrophil Elastase Native

<strong>Human Neutrophil Elastase Native</strong>_x000D_ <strong>Catalog number:</strong> B2017049_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> ELA-2, GE, NE, HLE, HNE, ELA2, SCN1, PMN-E_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Singh V, Singh N, Pradhan A, Kumar Y, Bhatnagar S. Structure-activity relationships of dihydropyrimidone inhibitors against native and auto-processed human neutrophil elastase Comput Biol Med. 2023 Jul;161:107004._x000D_ 2: Smith ET, Kruppa M, Johnson DA, Van Haeften J, Chen X, Leahy D, Peake J, Harris JM. High yield expression in Pichia pastoris of human neutrophil elastase fused to cytochrome B5 Protein Expr Purif. 2023 Jun;206:106255._x000D_ 3: Kafienah W, Buttle DJ, Burnett D, Hollander AP. Cleavage of native type I collagen by human neutrophil elastase Biochem J. 1998 Mar 1;330 ( Pt 2)(Pt 2):897-902._x000D_ 4: Barrett CD, Moore HB, Banerjee A, Silliman CC, Moore EE, Yaffe MB. Human neutrophil elastase mediates fibrinolysis shutdown through competitive degradation of plasminogen and generation of angiostatin J Trauma Acute Care Surg. 2017 Dec;83(6):1053-1061._x000D_ 5: Dahlen JR, Foster DC, Kisiel W. Inhibition of neutrophil elastase by recombinant human proteinase inhibitor 9 Biochim Biophys Acta. 1999 Sep 21;1451(2-3):233-41._x000D_ 6: Loke I, Østergaard O, Heegaard NHH, Packer NH, Thaysen-Andersen M. Paucimannose-Rich N-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions Mol Cell Proteomics. 2017 Aug;16(8):1507-1527._x000D_ 7: Piper MG, Massullo PR, Loveland M, Druhan LJ, Kindwall-Keller TL, Ai J, Copelan A, Avalos BR. Neutrophil elastase downmodulates native G-CSFR expression and granulocyte-macrophage colony formation J Inflamm (Lond). 2010 Jan 21;7(1):5._x000D_ 8: Kakuta Y, Aoshiba K, Nagai A. C-reactive protein products generated by neutrophil elastase promote neutrophil apoptosis Arch Med Res. 2006 May;37(4):456-60._x000D_ 9: Nogami K, Ogiwara K, Matsumoto T, Nishiya K, Takeyama M, Shima M. Mechanisms of human neutrophil elastase-catalysed inactivation of factor VIII(a) Thromb Haemost. 2011 Jun;105(6):968-80._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/2732232">10: Jordan RE, Nelson RM, Kilpatrick J, Newgren JO, Esmon PC, Fournel MA. Inactivation of human antithrombin by neutrophil elastase. Kinetics of the heparin-dependent reaction J Biol Chem. 1989 Jun 25;264(18):10493-500.</a>_x000D_ _x000D_ <strong>Products Related to Human Neutrophil Elastase Native can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>