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ARN 077 (enantiomer)

ARN 077 enantiomer (19) is the less active enantiomer of ARN 077, with an IC50 of 3.53 μM for rat NAAA[1].

Product Specifications

CAS Number

[1439366-88-7]

Product Name Alternative

URB913 (enantiomer)

UNSPSC

12352005

Target

Drug Isomer

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/arn-077-enantiomer.html

Purity

99.40

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OCCCCCC1=CC=CC=C1)N[C@H]2[C@H](OC2=O)C

Molecular Formula

C16H21NO4

Molecular Weight

291.34

References & Citations

[1]Stefano Ponzano, et al. Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors. J Med Chem. 2013 Sep 12;56 (17) :6917-34.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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