Osanetant
Osanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for schizophrenia[1].
Product Specifications
CAS Number
160492-56-8
Product Name Alternative
SR142801
UNSPSC
12352005
Hazard Statement
H302, H319
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/osanetant.html
Purity
98.19
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
O=C(N1C[C@@](CCCN2CCC(N(C(C)=O)C)(C3=CC=CC=C3)CC2)(C4=CC=C(Cl)C(Cl)=C4)CCC1)C5=CC=CC=C5
Molecular Formula
C35H41Cl2N3O2
Molecular Weight
606.62
Precautions
H302, H319
References & Citations
[1]Salomé N, et al. Selective blockade of NK2 or NK3 receptors produces anxiolytic- and antidepressant-like effects in gerbils. Pharmacol Biochem Behav. 2006 Apr;83 (4) :533-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
NK3R
Available Sizes
Frequently Asked Questions
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