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Osanetant

Osanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for schizophrenia[1].

Product Specifications

CAS Number

[160492-56-8]

Product Name Alternative

SR142801

UNSPSC

12352005

Hazard Statement

H302, H319

Target

Neurokinin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/osanetant.html

Purity

98.19

Solubility

DMSO : 66.67 mg/mL (ultrasonic)

Smiles

O=C(N1C[C@@](CCCN2CCC(N(C(C)=O)C)(C3=CC=CC=C3)CC2)(C4=CC=C(Cl)C(Cl)=C4)CCC1)C5=CC=CC=C5

Molecular Formula

C35H41Cl2N3O2

Molecular Weight

606.62

Precautions

H302, H319

References & Citations

[1]Salomé N, et al. Selective blockade of NK2 or NK3 receptors produces anxiolytic- and antidepressant-like effects in gerbils. Pharmacol Biochem Behav. 2006 Apr;83 (4) :533-9.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

NK3R

Available Sizes

Curated Selection

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