CDK4 degrader 1

12352005

CDK; Molecular Glues

Reference compound

Cell Cycle/DNA Damage; PROTAC

Cancer-Kinase/protease

Cancer

https://www.medchemexpress.com/cdk4-degrader-1.html

99.83

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

O=C(C1=CC2=CN=C(NC3=NC=C(N4CCN(S(=O)(C=C)=O)CC4)C=C3)N=C2N1C5CCCC5)N(C)C

C25H32N8O3S

524.64

[1]Lim M, et al. DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders[J]. ACS Central Science, 2024.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

Reference compound1

No Development Reported

CDK4