Serine Hydrolase inhibitor-21
Serine Hydrolase inhibitor-21 (compound 8), a pyridine, is a serine hydrolase inhibitor with a Ki of 429 nM for BuChE. Serine Hydrolase inhibitor-21 has the potential for Alzheimer's disease research[1].
Product Specifications
CAS Number
366448-34-2
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/serine-hydrolase-inhibitor-21.html
Purity
99.71
Solubility
DMSO : 12 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=CC(C(N2C3=C(C=CC=C3)SC4=CC=CC=C24)=O)=CN1
Molecular Formula
C18H12N2O2S
Molecular Weight
320.37
References & Citations
[1]Sultan Darvesh, et al. Novel pyridones and their use as modulators of serine hydrolase enzymes. WO2001077078A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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