Demecarium Bromide (Standard)

Demecarium Bromide (Standard) is the analytical standard of Demecarium Bromide. This product is intended for research and analytical applications. Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor, with an apparent affinity (Kiapp) of 0.15 μM[1]. Demecarium Bromide (BC-48) is used as a glaucoma agent[2].

Product Specifications

CAS Number

[56-94-0]

Product Name Alternative

BC-48 (Standard)

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Reference Standards

Type

Reference Standards

Related Pathways

Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/demecarium-bromide-standard.html

Smiles

O=C(N(CCCCCCCCCCN(C(OC1=CC([N+](C)(C)C)=CC=C1)=O)C)C)OC2=CC([N+](C)(C)C)=CC=C2.[Br-].[Br-]

Molecular Formula

C32H52Br2N4O4

Molecular Weight

716.59

References & Citations

[1]Brown JH, et al. Activation and blockade of cardiac muscarinic receptors by endogenous acetylcholine and cholinesterase inhibitors. J Pharmacol Exp Ther. 1982 Oct;223 (1) :20-4.|[2]Gum GG, et al. Effect of topically applied demecarium bromide and echothiophate iodide on intraocular pressure and pupil size in beagles with normotensive eyes and beagles with inherited glaucoma. Am J Vet Res. 1993 Feb;54 (2) :287-93.