Baquiloprim

Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria[1][2].

Product Specifications

CAS Number

[102280-35-3]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/baquiloprim.html

Solubility

10 mM in DMSO

Smiles

NC1=NC=C(CC2=C3C=CC=NC3=C(N(C)C)C(C)=C2)C(N)=N1

Molecular Formula

C17H20N6

Molecular Weight

308.38

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Lewicki J, et, al. Oral bioavailability and pharmacokinetics of baquiloprim in dwarf goats. Res Vet Sci. 1995 May;58 (3) :268-71.|[2]White DG, et, al. Comparison of danofloxacin with baquiloprim/sulphadimidine for the treatment of experimentally induced Escherichia coli diarrhoea in calves. Vet Rec. 1998 Sep 5;143 (10) :273-6.