Phenamacril
Phenamacril (JS399-19) inhibits activity of myosin I non-competitively with an IC50 of 360 nM through suppression of the ATPase activity, exhibits therefore an antifungal efficacy towards Fusarium species[1].
Product Specifications
CAS Number
39491-78-6
Product Name Alternative
JS399-19
UNSPSC
12352005
Target
Fungal; Myosin
Type
Reference compound
Related Pathways
Anti-infection; Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/phenamacril.html
Purity
99.55
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#C/C(C(OCC)=O)=C(C1=CC=CC=C1)/N
Molecular Formula
C12H12N2O2
Molecular Weight
216.24
References & Citations
[1]Wollenberg RD, et al., Phenamacril is a reversible and noncompetitive inhibitor of Fusarium class I myosin. J Biol Chem. 2019 Jan 25;294 (4) :1328-1337.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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