Phenamacril

Phenamacril (JS399-19) inhibits activity of myosin I non-competitively with an IC50 of 360 nM through suppression of the ATPase activity, exhibits therefore an antifungal efficacy towards Fusarium species[1].

Product Specifications

CAS Number

[39491-78-6]

Product Name Alternative

JS399-19

UNSPSC

12352005

Target

Fungal; Myosin

Type

Reference compound

Related Pathways

Anti-infection; Cytoskeleton

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/phenamacril.html

Purity

99.55

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N#C/C(C(OCC)=O)=C(C1=CC=CC=C1)/N

Molecular Formula

C12H12N2O2

Molecular Weight

216.24

References & Citations

[1]Wollenberg RD, et al., Phenamacril is a reversible and noncompetitive inhibitor of Fusarium class I myosin. J Biol Chem. 2019 Jan 25;294 (4) :1328-1337.