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CYP24A1 antibody

Product Specifications

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1, 25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

1,25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial (24-OHase, Vitamin D (3) 24-hydroxylase) |Cytochrome P450 24A1|Cytochrome P450-CC24|CYP24A1|CYP24

UniProt

Q07973

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Cytochrome P450, family 24, subfamily A, polypeptide 1

Target

CYP24A1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

43 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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