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SID7970631

SID7970631, as an isoquinolinone analog, is a potent and selective submicromolar SF-1 inhibitor (IC50=255 nM) . SID7970631 can be used for the research of cancer[1][2].

Product Specifications

CAS Number

868224-75-3

UNSPSC

12352005

Target

Orphan Nuclear Receptor; Orphan Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sid7970631.html

Purity

98.30

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(OC1=CC=CC2=C1C=CN(CC(NCC3=CC=C(OCO4)C4=C3)=O)C2=O)C(OCC)=O

Molecular Formula

C24H24N2O7

Molecular Weight

452.46

References & Citations

[1]Madoux F, et al. Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening. Mol Pharmacol. 2008;73 (6) :1776-1784.|[2]Doghman M, et al. Identification and characterization of steroidogenic factor-1 inverse agonists. Methods Enzymol. 2010;485:3-23.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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