SID7970631
SID7970631, as an isoquinolinone analog, is a potent and selective submicromolar SF-1 inhibitor (IC50=255 nM) . SID7970631 can be used for the research of cancer[1][2].
Product Specifications
CAS Number
868224-75-3
UNSPSC
12352005
Target
Orphan Nuclear Receptor; Orphan Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sid7970631.html
Purity
98.30
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(OC1=CC=CC2=C1C=CN(CC(NCC3=CC=C(OCO4)C4=C3)=O)C2=O)C(OCC)=O
Molecular Formula
C24H24N2O7
Molecular Weight
452.46
References & Citations
[1]Madoux F, et al. Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening. Mol Pharmacol. 2008;73 (6) :1776-1784.|[2]Doghman M, et al. Identification and characterization of steroidogenic factor-1 inverse agonists. Methods Enzymol. 2010;485:3-23.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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