What is the catalog number for GsAF-II?

The catalog number for GsAF-II is HY-P5177.

What sizes are available for GsAF-II?

GsAF-II is available in the following size(s): 1 Each.

GsAF-II is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GsAF-II?

GsAF-II is manufactured by QuantiMol.

What is the estimated delivery time for GsAF-II?

Estimated delivery time for GsAF-II is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GsAF-II?

The safety data sheet for GsAF-II is available here: http://file.medchemexpress.com/batch_PDF/HY-P5177/.

GsAF-II

GsAF-II is a peptide toxin that blocks hERG1 subtype potassium channels in a voltage-dependent manner. GsAF-II blocks Nav1.x subtype sodium channels[1].

Product Specifications

UNSPSC

12352209

Target

Potassium Channel; Sodium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/gsaf-ii.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CC(C)C)C(N[C@H]1C(C)C)=O)=O)=O)=O)NC2=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CCSC)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H]([C@H](O)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@H]7CC8=CNC9=CC=CC=C89)=O)=O)=O)NC1=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@H]2CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC%10=CNC%11=CC=CC=C%10%11)C(O)=O)=O)=O)=O)=O)=O)=O)NC7=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC%12=CC=C(C=C%12)O)N

Molecular Formula

C176H261N47O45S7

Molecular Weight

3979.70

References & Citations

[1]Redaelli E, et al. Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels. J Biol Chem. 2010 Feb 5;285 (6) :4130-4142.