Quinocarcin
Quinocarcin (DC-52) is a potent antitumor antibiotic. Quinocarcin inhibits Bacillus subtilis DNA, RNA and protein syntheses[1][2].
Product Specifications
CAS Number
84573-33-1
Product Name Alternative
Quinocarmycin; DC-52; KW2152 (free base)
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/quinocarcin.html
Smiles
O=C(O)[C@@H]1[C@]2([C@]([H])(N3[C@@]4(CO[C@]3([C@@]([H])(C1)N2C)[H])[H])CC5=C4C(OC)=CC=C5)[H]
Molecular Formula
C18H22N2O4
Molecular Weight
330.38
References & Citations
[1]Tomita F, et al. Quinocarcin, a novel antitumor antibiotic. 3. Mode of action. J Antibiot (Tokyo) . 1984 Oct;37 (10) :1268-72.|[2]Kahsai AW, et al. Quinocarmycin analog DX-52-1 inhibits cell migration and targets radixin, disrupting interactions of radixin with actin and CD44. Chem Biol. 2006 Sep;13 (9) :973-83.|[3]Plowman J, et al. Efficacy of the quinocarmycins KW2152 and DX-52-1 against human melanoma lines growing in culture kand in mice. Cancer Res. 1995 Feb 15;55 (4) :862-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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