Corylifol A
Product Specifications
UNSPSC Description
Corylifol A inhibits IL-6-induced STAT3 activation and phosphorylation, with an IC50 of 0.81 μM.
Target Antigen
STAT; UGT
Type
Natural Products
Related Pathways
JAK/STAT Signaling;Metabolic Enzyme/Protease;Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Corylifol-A.html
Purity
99.90
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C1C(C2=CC=C(O)C(C/C=C(C)/CC/C=C(C)\C)=C2)=COC3=CC(O)=CC=C13
Molecular Weight
390.47
References & Citations
[1]Lee SW, et al. Phenolic compounds isolated from Psoralea corylifolia inhibit IL-6-induced STAT3 activation. Planta Med. 2012 Jun;78(9):903-6.|[2]Kim DW, et al. Phenolic phytochemical displaying SARS-CoV papain-like protease inhibition from the seeds of Psoralea corylifolia. J Enzyme Inhib Med Chem. 2014 Feb;29(1):59-63.|[3]Li YG, et al. Fructus Psoraleae contains natural compounds with potent inhibitory effects towards human carboxylesterase 2. Fitoterapia. 2015 Jan 13;101C:99-106. d
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0897/Corylifol-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0897/Corylifol-A-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
775351-88-7
Available Sizes
Curated Selection
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