Cilazapril (Standard)

Cilazapril (Standard) is the analytical standard of Cilazapril (HY-A0043) . This product is intended for research and analytical applications. Cilazapril is an orally active prodrug of the angiotensin-converting enzyme (ACE) inhibitor Cilazaprilat (HY-A0113) . Cilazapril reduces plasma ACE activity. Cilazapril can be used in the research of hypertension (including essential and renal hypertension) and congestive heart failure[1][2][3][4][5].

Product Specifications

CAS Number

[88768-40-5]

Product Name Alternative

Ro 31-2848 (Standard)

UNSPSC

12352005

Target

Angiotensin-converting Enzyme (ACE) ; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/cilazapril-standard.html

Smiles

O=C([C@@H]1CCCN2N1C([C@@H](N[C@@H](CCC3=CC=CC=C3)C(OCC)=O)CCC2)=O)O

Molecular Formula

C22H31N3O5

Molecular Weight

417.50

References & Citations

[1]Szucs, T., Cilazapril. A review. Drugs, 1991. 41 Suppl 1: p. 18-24.|[2]Nussberger, J., et al., Repeated administration of the converting enzyme inhibitor cilazapril to normal volunteers. J Cardiovasc Pharmacol, 1987. 9 (1) : p. 39-44.