VS-15
VS-15, a IDO1 inhibitor, selectively binds the heme-free form of IDO1. VS-15 is described as an iNOS inhibitor based on the reduction of NO production[1].
Product Specifications
CAS Number
951948-78-0
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO) ; NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vs-15.html
Smiles
O=C(NCCC1=CNC2=C1C=CC=C2)C3=C(NC(C(NCCC4=CNC5=C4C=CC=C5)=O)=O)C=CC=C3
Molecular Formula
C29H27N5O3
Molecular Weight
493.56
References & Citations
[1]Eleonora Panfili, et al. Identification of a Compound Inhibiting Both the Enzymatic and Nonenzymatic Functions of Indoleamine 2,3-Dioxygenase 1. ACS Pharmacol Transl Sci. 2024 Sep 12;7 (10) :3056-3070.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
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