Phenylacetylglycine (Highly Pure)

<strong>Phenylacetylglycine (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2017504_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 193.2_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> NSC 408424, NSC 92778, PAG, PAGly, Phenaceturic Acid, N-Phenylacetylglycine_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Nemet I, Saha PP, Gupta N, Zhu W, Romano KA, Skye SM, Cajka T, Mohan ML, Li L, Wu Y, Funabashi M, Ramer-Tait AE, Naga Prasad SV, Fiehn O, Rey FE, Tang WHW, Fischbach MA, DiDonato JA, Hazen SL. A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors Cell. 2020 Mar 5;180(5):862-877.e22._x000D_ 2: Romano KA, Nemet I, Prasad Saha P, Haghikia A, Li XS, Mohan ML, Lovano B, Castel L, Witkowski M, Buffa JA, Sun Y, Li L, Menge CM, Demuth I, König M, Steinhagen-Thiessen E, DiDonato JA, Deb A, Bäckhed F, Tang WHW, Naga Prasad SV, Landmesser U, Van Wagoner DR, Hazen SL. Gut Microbiota-Generated Phenylacetylglutamine and Heart Failure Circ Heart Fail. 2023 Jan;16(1):e009972._x000D_ 3: Xu X, Lu WJ, Shi JY, Su YL, Liu YC, Wang L, Xiao CX, Chen C, Lu Q. The gut microbial metabolite phenylacetylglycine protects against cardiac injury caused by ischemia/reperfusion through activating β2AR Arch Biochem Biophys. 2021 Jan 15;697:108720._x000D_ 4: Zhu Y, Dwidar M, Nemet I, Buffa JA, Sangwan N, Li XS, Anderson JT, Romano KA, Fu X, Funabashi M, Wang Z, Keranahalli P, Battle S, Tittle AN, Hajjar AM, Gogonea V, Fischbach MA, DiDonato JA, Hazen SL. Two distinct gut microbial pathways contribute to meta-organismal production of phenylacetylglutamine with links to cardiovascular disease Cell Host Microbe. 2023 Jan 11;31(1):18-32.e9._x000D_ 5: Delaney J, Neville WA, Swain A, Miles A, Leonard MS, Waterfield CJ. Phenylacetylglycine, a putative biomarker of phospholipidosis: its origins and relevance to phospholipid accumulation using amiodarone treated rats as a model Biomarkers. 2004 May-Jun;9(3):271-90._x000D_ 6: Kristiansen RG, Rose CF, Fuskevåg OM, Mæhre H, Revhaug A, Jalan R, Ytrebø LM. L-Ornithine phenylacetate reduces ammonia in pigs with acute liver failure through phenylacetylglycine formation: a novel ammonia-lowering pathway Am J Physiol Gastrointest Liver Physiol. 2014 Nov 15;307(10):G1024-31._x000D_ 7: Kamiguchi H, Yamaguchi M, Murabayashi M, Mori I, Horinouchi A. Method development and validation for simultaneous quantitation of endogenous hippuric acid and phenylacetylglycine in rat urine using liquid chromatography coupled with electrospray ionization tandem mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Nov 1;1035:76-83._x000D_ 8: Doessegger L, Schmitt G, Lenz B, Fischer H, Schlotterbeck G, Atzpodien EA, Senn H, Suter L, Csato M, Evers S, Singer T. Increased levels of urinary phenylacetylglycine associated with mitochondrial toxicity in a model of drug-induced phospholipidosis Ther Adv Drug Saf. 2013 Jun;4(3):101-14._x000D_ 9: Park S, Belfoul AM, Rastelli M, Jang A, Monnoye M, Bae H, Kamitakahara A, Giavalisco P, Sun S, Barelle PY, Plows J, Jang C, Fodor A, Goran MI, Bouret SG. Maternal low-calorie sweetener consumption rewires hypothalamic melanocortin circuits via a gut microbial co-metabolite pathway JCI Insight. 2023 May 22;8(10):e156397._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/35487889">10: Pu J, Liu Y, Gui S, Tian L, Yu Y, Wang D, Zhong X, Chen W, Chen X, Chen Y, Chen X, Gong X, Liu L, Li W, Wang H, Xie P. Effects of pharmacological treatment on metabolomic alterations in animal models of depression Transl Psychiatry. 2022 Apr 29;12(1):175. </a>_x000D_ _x000D_ <strong>Products Related to Phenylacetylglycine (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>