Iturin A
Product Specifications
UNSPSC Description
Iturin A is a cyclic lipid peptide with strong antifungal activity. Iturin A induces ROS explosion and induces apoptosis and autophagy in tumor cells. Iturin A has antitumor activity[1][2].
Target Antigen
Apoptosis; Autophagy; Fungal; Reactive Oxygen Species
Type
Peptides
Related Pathways
Anti-infection;Apoptosis;Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/iturin-a.html
Purity
98.53
Solubility
Ethanol : 5 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CC(N)=O)C(N[C@H](CC1=CC=C(O)C=C1)C(N[C@H](CC(N)=O)C(N[C@@H](CCC(N)=O)C(N2CCC[C@H]2C(N[C@H](CC(N)=O)C(N[C@@H](CO)C(N3)=O)=O)=O)=O)=O)=O)=O)C[C@@H]3CCCCCCCC[R]
References & Citations
[1]Gong AD, et al. Antagonistic mechanism of iturin A and plipastatin A from Bacillus amyloliquefaciens S76-3 from wheat spikes against Fusarium graminearum. PLoS One. 2015 Feb 17;10(2):e0116871.|[2]Zhao H, et al. Effects of Bacillus subtilis iturin A on HepG2 cells in vitro and vivo. AMB Express. 2021 May 10;11(1):67.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2322/Iturin-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2322/Iturin-A-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
52229-90-0
Available Sizes
Curated Selection
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