IE-DAP
IE-DAP is a Nod1 agonist. Nod1 recognition of iE-DAP can activate the NF-κB pathway, leading to an inflammatory cytokine response. iE-DAP can be used for the research of maternal-fetal inflammation and preterm labor[1].
Product Specifications
CAS Number
[592520-07-5]
UNSPSC
12352209
Target
NOD-like Receptor (NLR)
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ie-dap.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C(N)CCCC(NC(CC[C@@H](N)C(O)=O)=O)C(O)=O
Molecular Formula
C12H21N3O7
Molecular Weight
319.31
References & Citations
[1]Cardenas I, et al. Nod1 activation by bacterial iE-DAP induces maternal-fetal inflammation and preterm labor. J Immunol. 2011 Jul 15;187 (2) :980-6.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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