Glycerophosphoinositol (choline)

Glycerophosphoinositol choline is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders[1][2].

Product Specifications

CAS Number

[425642-32-6]

UNSPSC

12352211

Target

Endogenous Metabolite; nAChR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/glycerophosphoinositol-choline.html

Purity

98.0

Solubility

H2O : 5 mg/mL (ultrasonic)

Smiles

C[N+](C)(C)CCO.OC[C@@H](O)COP(O[C@H]1[C@@H]([C@H]([C@@H]([C@H]([C@H]1O)O)O)O)O)([O-])=O

Molecular Formula

C14H32NO12P

Molecular Weight

437.38

References & Citations

[1] M Q Holmes-McNary, et al. Apoptosis is induced by choline deficiency in fetal brain and in PC12 cells. Brain Res Dev Brain Res. 1997 Jul 18;101 (1-2) :9-16.|[2] T J Rowley, et al. Antinociceptive and anti-inflammatory effects of choline in a mouse model of postoperative pain. Br J Anaesth. 2010 Aug;105 (2) :201-7.