N-Acetylcarnosine
N-Acetylcarnosine, a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic agent in human cataracts[1].
Product Specifications
CAS Number
56353-15-2
Product Name Alternative
N-Acetyl-L-carnosine
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Drug Intermediate; Endogenous Metabolite
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/n-acetylcarnosine.html
Concentration
10mM
Purity
99.92
Solubility
H2O : 250 mg/mL (ultrasonic)
Smiles
OC([C@@H](NC(CCNC(C)=O)=O)CC1=CNC=N1)=O
Molecular Formula
C11H16N4O4
Molecular Weight
268.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Babizhayev MA, et al. N-Acetylcarnosine, a natural histidine-containing dipeptide, as a potent ophthalmic drug in treatment of human cataracts. Peptides. 2001 Jun;22 (6) :979-94.|[2]Dubois VD, et al. N-acetylcarnosine (NAC) drops for age-related cataract. Cochrane Database Syst Rev. 2017 Feb 28;2:CD009493.|[3]Babizhayev MA, et al. Potentiation of intraocular absorption and drug metabolism of N-acetylcarnosine lubricant eye drops: drug interaction with sight threatening lipid peroxides in the treatment for age-related eye diseases. Drug Metabol Drug Interact. 2009;24 (2-4) :275-323.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Frequently Asked Questions
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