IL-18R alpha, Rat (HEK293, Fc)
Selected Variant
HY-P76423
Size: 1 Each
IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines[1]. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ[2]. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18[3]. IL-18R alpha Protein, Rat (HEK293, Fc) is a recombinant protein with hFc tag and is produced by HEK293 cells.
Product Specifications
Product Name Alternative
IL-18R alpha Protein, Rat (HEK293, Fc), Rat, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/il-18r-alpha-protein-rat-hek293-fc.html
Molecular Formula
301365 (Gene_ID) D3ZRM2 (A18-G326) (Accession)
Molecular Weight
Approximately 105 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
References & Citations
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
Price
Frequently Asked Questions
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