Tetomilast
Product Specifications
UNSPSC Description
Tetomilast (OPC-6535) is a PDE4 inhibitor with potential for the research of inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD).
Target Antigen
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tetomilast.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
CCOC1=C(OCC)C=CC(C2=NC(C3=CC=CC(C(O)=O)=N3)=CS2)=C1
Molecular Weight
370.42
References & Citations
[1]Ichikawa H, Okamoto S, Kamada N, et al. Tetomilast suppressed production of proinflammatory cytokines from human monocytes and ameliorated chronic colitis in IL-10-deficient mice. Inflamm Bowel Dis. 2008;14(11):1483-1490.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-105092/Tetomilast-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-105092/Tetomilast-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
145739-56-6
Available Sizes
Curated Selection
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