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GR144053 (trihydrochloride)

GR 144053 trihydrochloride is a selective and non-peptic GPIIb/IIIa inhibitor (IC50=37 nM) [1].

Product Specifications

CAS Number

1215333-48-4

UNSPSC

12352005

Target

Integrin

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/gr144053-trihydrochloride.html

Solubility

10 mM in DMSO

Smiles

OC(CN1CCC(N2CCN(C3=CC=C(C(N)=N)C=C3)CC2)CC1)=O.[H]Cl.[H]Cl.[H]Cl

Molecular Formula

C18H30Cl3N5O2

Molecular Weight

454.82

References & Citations

[1]Uhl B, et al. Vitronectin promotes immunothrombotic dysregulation in the venular microvasculature. Front Immunol. 2023 Feb 8;14:1078005.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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