11-Hydroxytephrosin
11-Hydroxytephrosin is a potent inhibitor of NF-kappaB. NF-kappaB is known to play a crucial role in the regulation of genes controlling the immune system, apoptosis, tumor cell growth, and tissue differentiation[1].
Product Specifications
CAS Number
72458-85-6
UNSPSC
12352005
Target
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/11-hydroxytephrosin.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C1[C@]2(O)[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC(O)=C14
Molecular Formula
C23H22O8
Molecular Weight
426.42
References & Citations
[1]Dat NT, et al. Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression. J Nat Prod. 2008;71 (10) :1696-1700.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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