(Rac) -Sclerone

(Rac) -Sclerone is a natural product, that can be isolated from the green husk of Carya illinoinensis. (Rac) -Sclerone shows appreciable inhibition of AChE, with an IC50 of 192.65 ± 10.12 μg/mL[1].

Product Specifications

CAS Number

[19638-58-5]

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Cholinesterase (ChE)

Type

Natural Products

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rac-sclerone.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(C(CC1)O)C(O)=CC=C2

Molecular Formula

C10H10O3

Molecular Weight

178.18

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Devidas SB, et al. Two undescribed diarylheptanoids from green husk of Carya illinoinensis as acetylcholinesterase inhibitors. Nat Prod Res. 2022 Mar;36 (5) :1161-1169.