Human GIPR Protein, His, Flag Tag (Detergent)
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011]
Product Specifications
Background
Specifications
This protein carries a polyhistidine tag and a Flag tag at the C-terminus. The protein has a calculated MW of 69.5 kDa.
Accession Number
P48546-1
Expression Region
Arg 22 - Cys 466
Host
HEK293
Target
GIPR
Conjugation
Unconjugated
Tag
C-10xHis & C-Flag
Source
Human
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Format
Liquid
Buffer
50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Additives
Glycerol
Molecular Weight
69.5 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
500ug*1
Host or Source
HEK293
Species
Human
Protein ID
P48546-1
Preservative
Glycerol
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