COX-2-IN-2
COX-2-IN-2 is a selective and inducible COX2 inhibitor with an IC50 of 0.24 μM. COX-2-IN-1 is an anti-inflammatory compound with anti-inflammatory and analgesic activities.
Product Specifications
CAS Number
[134729-13-8]
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/1-_4-fluorophenyl_-5-[4-_methylsulfonyl_phenyl]-pyrazole-3-carbonitrile.html
Purity
99.53
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
N#CC1=NN(C2=CC=C(F)C=C2)C(C3=CC=C(S(=O)(C)=O)C=C3)=C1
Molecular Formula
C17H12FN3O2S
Molecular Weight
341.36
References & Citations
[1]Tsuji K, et al. Studies on anti-inflammatory agents. IV. Synthesis and pharmacological properties of 1,5-diarylpyrazoles and related derivatives. Chem Pharm Bull (1997), 45 (6), 987-995.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2
Available Sizes
Curated Selection
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