YPLP
YPLP is a yeast-derived peptide Tyr-Pro-Leu-Pro, which exhibits activity in anti fatigue mechanisms through the nuclear factor erythroid-2-related factor 2 (Nrf2) - and AMP-activated protein kinase (AMPK) pathway. YPLP is orally active[1].
Product Specifications
CAS Number
2414391-44-7
UNSPSC
12352209
Target
AMPK; Keap1-Nrf2
Type
Reference compound
Related Pathways
Epigenetics; NF-κB; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/yplp.html
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(N2[C@@H](CCC2)C(O)=O)=O)=O)[C@H](CC3=CC=C(C=C3)O)N
Molecular Formula
C25H36N4O6
Molecular Weight
488.58
References & Citations
[1]Cai J, et al., Studying Antifatigue Mechanism of Tyr-Pro-Leu-Pro in Exercise Mice Using Label-Free Proteomics. J Agric Food Chem. 2024 Jan 31;72 (4) :2178-2192.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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