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Recombinant Human TRIM21/RO52 Protein

Ro52 antigen is an E3-ubiquitin-ligase. Anti-Ro52 Abs are present in patients with a broad spectrum of autoimmune diseases. Usually these Abs are in association with anti-Ro60 in lupus erythematosus (SLE) and Sjögren syndrome (SS) . In addition, anti-Ro52 is also frequently present in inflammatory myositis.

Product Specifications

Product Name Alternative

SS-A, E3 ubiquitin-protein ligase TRIM21, TRIM21, Ro (SS-A), 52 kDa Ro protein, Tripartite motif-containing protein 21, RING finger protein 81, 52 kDa ribonucleoprotein autoantigen Ro/SS-A, RNF81, Sjoegren syndrome type A antigen, RO52, RING-type E3 ubiquitin transferase TRIM21, SSA1

Accession Number

P19474

Expression System

Confidential

Nature

Recombinant

Applications

As a diagnostic tool for Systemic Lupus Erythematosus (SLE) and Sjögren Syndrome (SS) .

Stability

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Endotoxin

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Form

Lyophilized

Buffer

Lyophilized from a solution in PBS pH 7.4,1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution.

Shipping Conditions

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Notes

For research use only.

Species

Homo sapiens (Human)

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