Endothelial lipase inhibitor-1
Endothelial lipase inhibitor-1 is a potent endothelial lipase inhibitor with an IC50 of 49 nM.
Product Specifications
CAS Number
1466427-02-0
UNSPSC
12352005
Target
Lipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Endothelial_lipase_inhibitor-1.html
Purity
98.02
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(C(NC(N1)=O)=C(N)C1=O)N[C@H]2C3=C(C(OCC4=CC=CC=C4)=CC=C3)CCC2
Molecular Formula
C22H22N4O4
Molecular Weight
406.43
References & Citations
[1]Hu CH, et al. Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors. Bioorg Med Chem Lett. 2018 Dec 15;28 (23-24) :3721-3725.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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