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Lornoxicam (Standard)

Lornoxicam (Standard) is the analytical standard of Lornoxicam. This product is intended for research and analytical applications. Lornoxicam (Chlortenoxicam) is a highly active COX-1 and COX-2 inhibitor with IC50 of 5 nM and 8 nM respectively. It is a new non-steroidal anti-inflammatory compound.

Product Specifications

CAS Number

70374-39-9

Product Name Alternative

Chlortenoxicam (Standard) ; Ro 13-9297 (Standard)

UNSPSC

12352005

Target

COX; Endogenous Metabolite; Reference Standards

Type

Reference Standards

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/lornoxicam-standard.html

Smiles

O=C(C1=C(O)C2=C(C=C(Cl)S2)S(N1C)(=O)=O)NC3=NC=CC=C3

Molecular Formula

C13H10ClN3O4S2

Molecular Weight

371.82

References & Citations

[1]Spyra S, et al. COX-2-selective inhibitors celecoxib and deracoxib modulate transient receptor potential vanilloid 3 channels. Br J Pharmacol. 2017 Aug;174 (16) :2696-2705.|[2]Rose, P. and C. Steinhauser, Comparison of Lornoxicam and Rofecoxib in Patients with Activated Osteoarthritis (COLOR Study) . Clin Drug Investig, 2004. 24 (4) : p. 227-36.|[3]Bianchi, M. and A.E. Panerai, Effects of lornoxicam, piroxicam, and meloxicam in a model of thermal hindpaw hyperalgesia induced by formalin injection in rat tail. Pharmacol Res, 2002. 45 (2) : p. 101-5.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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