TEI-6472
TEI-6472, a naphthalene derivative, can suppress IgE responses both in vitro and in vivo. TEI-6472 causes significant inhibition of FceRI-mediated histamine release[1].
Product Specifications
CAS Number
151379-49-6
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tei-6472.html
Smiles
NCCCC[C@H](N)C(O)=O.OC(C(C=CC=C1)=C1NC(CCC[C@H](C2)[C@@H]2/C=C/C3=CC4=C(C=CC=C4)C=C3)=O)=O
Molecular Formula
C32H39N3O5
Molecular Weight
545.67
References & Citations
[1]H Ohmori, et al. Suppression of IgE antibody response in mice by a naphthalene derivative, TEI-6472. Int J Immunopharmacol. 1993 Jul;15 (5) :573-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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